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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMEL1 All Species: 30.91
Human Site: Y688 Identified Species: 61.82
UniProt: Q495T6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q495T6 NP_258428.2 779 89367 Y688 N G G V R Q A Y K A Y L K W M
Chimpanzee Pan troglodytes XP_001150860 781 89158 Y690 N G G V R Q A Y K A Y L K W M
Rhesus Macaque Macaca mulatta XP_001105708 750 85452 Y659 N G G I G Q A Y R A Y Q N Y V
Dog Lupus familis XP_546737 807 92419 Y716 N G G V R Q A Y K A Y L K W M
Cat Felis silvestris
Mouse Mus musculus Q9JLI3 765 88681 Y674 N G G V R Q A Y K A Y L R W L
Rat Rattus norvegicus P0C1T0 774 89178 Y683 N G G V R Q A Y K A Y L Q W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233077 749 86047 Y658 N G G V R Q A Y Q A Y L K W L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689191 755 86752 Y664 N G G V R Q A Y K A Y V K W V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511056 849 96515 F758 N G G L K Q A F R A Y K K W E
Honey Bee Apis mellifera XP_392502 776 89056 F685 N G G L K Q S F R A Y K K W V
Nematode Worm Caenorhab. elegans O16796 848 97043 F756 N G G V K E A F Q A Y Q K Y V
Sea Urchin Strong. purpuratus XP_781407 763 86739 F671 N G G L K Q A F R A Y K T I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.9 50.8 82.6 N.A. 77 77.6 N.A. N.A. 66.2 N.A. 59.9 N.A. 39 40.5 35 38.1
Protein Similarity: 100 97.1 72 89 N.A. 88.6 88.8 N.A. N.A. 81.6 N.A. 77.6 N.A. 55.9 59.8 54.1 58.5
P-Site Identity: 100 100 53.3 100 N.A. 86.6 86.6 N.A. N.A. 86.6 N.A. 86.6 N.A. 60 53.3 53.3 46.6
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 86.6 93.3 93.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 92 0 0 100 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % F
% Gly: 0 100 100 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 34 0 0 0 50 0 0 25 67 0 0 % K
% Leu: 0 0 0 25 0 0 0 0 0 0 0 50 0 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % M
% Asn: 100 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 92 0 0 17 0 0 17 9 0 0 % Q
% Arg: 0 0 0 0 59 0 0 0 34 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 0 67 0 0 0 0 0 0 0 9 0 0 42 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 100 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _